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Gene Page - CG Number : CG11968
Gene Summary - CG11968:

CG11968: This gene is referred to in FlyBase by the symbol Dmel\RagA (CG11968, FBgn0037647). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein heterodimerization activity. There is experimental evidence that it is involved in the biological process: positive regulation of cell growth; positive regulation of TOR signaling cascade; cellular response to starvation; regulation of autophagy. 7 alleles are reported. The phenotypes of these alleles are annotated with: wing; autophagic vacuole. It has one annotated transcript and one annotated polypeptide. Protein features are: Gtr1/RagA G protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.

Gene summary for CG11968 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11968:CG11968 is not perturbed in primary screen.
CG11968 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11968.
Cell Count:
CG_NumberCategoryR1R2R3
CG11968Primary screen209229228
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11968:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22134-0.076705507-0.1749547020.521260068-1.135311939-0.670750957-0.5526256611.239058405-0.064868676-1.30108311-1.058646343-0.23147876-0.525522047-0.911931075-0.06097029-0.761838162-0.238718566-1.547108568-1.405452158-1.787203273-0.7665914690.324753964-0.145325988-0.316205457
2221922.0045616621.2365631190.2990976811.450875077-0.522715403-0.4255881561.852855493-0.592246364-0.3832286630.8068421360.9315085760.199353495-1.260961106-0.463078342.625942907-1.128026127-1.1152290011.493732255-0.999463536-0.2147678280.2027888193.5030037461.172256269
223102-0.416146046-0.490774213-0.9192906260.26561124-0.7151408230.289175276-0.3515419220.586887035-0.2983413840.412134112-0.0868952590.887112147-0.992428376-0.13265946-1.113122916-0.531413801-0.937833016-1.108994745-0.91541309-0.3299864480.6230874710.6573950530.61963439
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11968 is not tested in classification assay
Integrated Annotations for CG11968 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
positive regulation of cell growthGO:0030307inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from electronic annotation with InterPro:IPR006762
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
GTPase activityGO:0003924inferred from sequence or structural similarity with UniProtKB:Q15347
GTP binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG11968 in FlyBase
FLIGHTClick here to see CG11968 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11968 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11968
Entrez GeneEntrez Gene page for CG11968
UniprotUniprot page for CG11968

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)