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Gene Page - CG Number : CG11987
Gene Summary - CG11987:

CG11987: The gene tango is referred to in FlyBase by the symbol Dmel\tgo (CG11987, FBgn0264075). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; protein binding; sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein heterodimerization activity. There is experimental evidence for 12 unique biological process terms, many of which group under: system development; biological regulation; multicellular organismal development; regulation of RNA metabolic process; neuron differentiation; cellular process; cellular component organization or biogenesis; localization; response to hormone stimulus; cellular response to decreased oxygen levels. 31 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system; organ system subdivision; late extended germ band embryo; non-connected developing system; peripheral nervous system; tracheal branch primordium; multicellular structure; portion of tissue; tracheal system; dorsal trunk primordium; dorsal branch primordium; eo support cell; lamina forming neuroblast; cell part; ventral nerve cord primordium; embryonic/larval neuron; adult segment. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Helix-loop-helix domain; Nuclear translocator; PAC motif; PAS domain; PAS fold; PAS fold-3. Gene sequence location is 3R:4842495..4845744.

Gene summary for CG11987 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11987:CG11987 is not perturbed in primary screen.
CG11987 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fint2+ LP_Fint4+ Okt+(fld) Rto3+ SP_Fint1+ SP_Fint2+ SP_Fint3+
CG11987 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11987.
Cell Count:
CG_NumberCategoryR1R2R3
CG11987Primary screen53275480
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11987:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221433.1880693246.2265697175.7178245690.7094353540.8658347447.56658917210.196220559.0285036964.2065146991.1823069032.162938073-0.1602556611.4668987321.46342627-0.042294042-0.0756274152.5058801522.3409106191.2243303335.024293198-0.3856656295.7259706694.885484956
222183-1.246838069-0.156587065-0.856990483-0.462405849-2.111110748-0.737539886-1.648645551-0.227290896-3.80995015-0.576245052-0.9265431990.615828633-1.0516292650.5663910690.588407412-1.959604422-0.923263893-1.658336520.175162015-3.567985584-0.480469385-0.935799505-0.192695465
223931.296300917-0.206772808-0.3723059610.5424296530.4579010111.234162280.3958729881.4529342981.5216592620.350630188-0.3014023880.325548337-0.287765258-0.0436332810.1442053241.162407315-0.086510637-1.0529295130.7124171161.172746392-0.089094284-0.0361448550.786608466
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG11987Slide9C0.1621.1041.2501.091
CG11987Slide9O0.0431.4351.1811.415
CG11987Slide9P0.0051.3301.3491.413
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG11987 :Gene Ontology Annoations: Biological Process
Gene Ontology Annoations: Cellular Component
Gene Ontology Annoations: Molecular Function
Other annotations
DatabaseLink
FlyBaseClick here to see CG11987 in FlyBase
FLIGHTClick here to see CG11987 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11987 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11987
Entrez GeneEntrez Gene page for CG11987
UniprotUniprot page for CG11987

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)