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Gene Page - CG Number : CG11992
Gene Summary - CG11992:

CG11992: The gene Relish is referred to in FlyBase by the symbol Dmel\Rel (CG11992, FBgn0014018). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; DNA binding. There is experimental evidence for 14 unique biological process terms, many of which group under: biological regulation; positive regulation of cellular biosynthetic process; response to stress; immune system process; immune response; positive regulation of cellular metabolic process; defense response to bacterium; positive regulation of cellular amide metabolic process; positive regulation of biological process; response to other organism; response to bacterium; response to nutrient levels; neuron differentiation. 63 alleles are reported. The phenotypes of these alleles are annotated with: adult posterior midgut epithelium; macrochaeta; mesothoracic tergum. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Cell surface receptor IPT/TIG; Immunoglobulin E-set; Immunoglobulin-like fold; NF-kappa-B/Rel/dorsal; Rel homology; p53-like transcription factor, DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages.

Gene summary for CG11992 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG11992:CG11992 is perturbed in following parameters in primary screen: CellSize
CG11992 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG11992.
Cell Count:
CG_NumberCategoryR1R2R3
CG11992Primary screen423169213
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG11992:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221471.662305743-0.066300754-0.5090640740.4312376150.1499198130.6218674720.7924308350.4820019810.1702641970.833462785-0.1166798940.4212371890.0571123840.0107310891.8412477090.180750286-1.024494219-0.387392652-1.1142200580.500967340.0671881582.068839583-0.163083897
2222090.24884743-0.650787403-0.64588108-0.462981826-1.765871551-0.8200455650.062787793-0.708184969-0.7803254960.2007605360.125926984-0.0901773351.245132527-0.719200327-0.368028633-1.448635462.7500897230.832656135-0.777514145-0.6543031673.257622551-0.94853631-0.169502993
223119-0.7449227110.068889517-0.6299266320.350236419-0.23145728-1.473595526-1.530261195-1.608262634-0.6553284350.667393873-0.105364228-0.472304996-0.502959762-0.250325889-0.194654315-0.2230040890.3351125060.8298530660.073196732-0.948292313.477629245-0.397602020.362331535
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG11992 is not tested in classification assay
Integrated Annotations for CG11992 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
positive regulation of antibacterial peptide biosynthetic processGO:0006963inferred from expression pattern
positive regulation of antibacterial peptide biosynthetic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from direct assay
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with Dredd
sequence-specific DNA binding transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG11992 in FlyBase
FLIGHTClick here to see CG11992 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG11992 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG11992
Entrez GeneEntrez Gene page for CG11992
UniprotUniprot page for CG11992

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)