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Gene Page - CG Number : CG1200
Gene Summary - CG1200:

CG1200: The gene APP-like protein interacting protein 1 is referred to in FlyBase by the symbol Dmel\Aplip1 (CG1200, FBgn0040281). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; protein kinase binding; kinesin binding. There is experimental evidence that it is involved in the biological process: axon transport of mitochondrion; neuron projection morphogenesis; regulation of JNK cascade; retrograde synaptic vesicle transport; anterograde synaptic vesicle transport. 13 alleles are reported. The phenotypes of these alleles are annotated with: mitochondrion; axon. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Phosphotyrosine interaction domain; Pleckstrin homology-like domain; Src homology-3 domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages.

Gene summary for CG1200 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1200:CG1200 is perturbed in following parameters in primary screen: Tclc
CG1200 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1200.
Cell Count:
CG_NumberCategoryR1R2R3
CG1200Primary screen457759419
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1200:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG1200 is not tested in classification assay
Integrated Annotations for CG1200 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
anterograde synaptic vesicle transportGO:0048490inferred from mutant phenotype
axon transport of mitochondrion
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737non-traceable author statement
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
kinesin bindingGO:0019894non-traceable author statement
protein kinase binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG1200 in FlyBase
FLIGHTClick here to see CG1200 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1200 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1200
Entrez GeneEntrez Gene page for CG1200
UniprotUniprot page for CG1200

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)