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Gene Page - CG Number : CG12002
Gene Summary - CG12002:

CG12002: The gene Peroxidasin is referred to in FlyBase by the symbol Dmel\Pxn (CG12002, FBgn0011828). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: peroxidase activity. There is experimental evidence that it is involved in the biological process: phagocytosis; extracellular matrix organization. 10 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Haem peroxidase; Haem peroxidase, animal; Haem peroxidase, animal, subgroup; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Leucine-rich repeat, typical subtype; Leucine-rich repeat-containing N-terminal; von Willebrand factor, type C. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages.

Gene summary for CG12002 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12002:CG12002 is not perturbed in primary screen.
CG12002 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12002.
Cell Count:
CG_NumberCategoryR1R2R3
CG12002Primary screen274437348
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12002:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22152-0.511608024-0.8643132680.64766271-0.798137014-0.32649486-2.263730113-1.391759069-1.534546058-2.107298689-0.563732308-0.201489975-0.420600461-0.10863078-0.256750741.287656621-0.586742716-1.066945337-0.888236149-1.185928707-1.870486605-0.274174180.6854343982.266411775
222204-0.2070355340.0951405671.454587769-0.514723967-0.1422398061.9041694083.2075122721.2861992442.2013517660.6070998682.485024568-0.3099985721.3106756760.302071965-0.901461584-0.1215939940.6853106361.9145907840.6626069382.764626509-0.184232276-0.0340835850.219387922
2231140.0472467120.184417996-0.010133491-0.1039586040.0397132751.2633853860.6424156631.4265993612.078418869-0.2497916830.371045272-0.163892778-0.0303895680.4270906490.5906244630.3384176680.990131041.1490452370.2335947621.6584536220.12708667-0.172692615-0.338235663
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12002 is not tested in classification assay
Integrated Annotations for CG12002 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
oxidation-reduction processGO:0055114inferred from electronic annotation with InterPro:IPR002007, InterPro:IPR010255, InterPro:IPR019791
response to oxidative stress
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
proteinaceous extracellular matrixGO:0005578inferred from sequence or structural similarity
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
peroxidase activityGO:0004601inferred from sequence or structural similarity with MGD:Mpo; MGI:MGI:97137
heme binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG12002 in FlyBase
FLIGHTClick here to see CG12002 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12002 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12002
Entrez GeneEntrez Gene page for CG12002
UniprotUniprot page for CG12002

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)