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Gene Page - CG Number : CG12013
Gene Summary - CG12013:

CG12013: The gene PHGPx is referred to in FlyBase by the symbol Dmel\PHGPx (CG12013, FBgn0035438). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: peroxidase activity. There is experimental evidence that it is involved in the biological process: response to oxidative stress. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Glutathione peroxidase; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG12013 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12013:CG12013 is not perturbed in primary screen.
CG12013 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12013.
Cell Count:
CG_NumberCategoryR1R2R3
CG12013Primary screen313291166
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12013:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221580.1215516930.0493105010.6308707450.9603016211.413034672.0883471712.6241767491.6967642132.5837769341.502622092.386987237-0.1261966091.8844863091.485301094-0.063658042.6776016543.6515740713.7080076712.7961008512.6213733381.5612383392.226788320.371344339
2221980.3797294840.8031451731.612146869-0.4171006011.3560869073.0421138464.7884227063.2754593331.9940556970.4154626012.041202751-0.0292651851.5865744291.3183019360.2783663941.325230591.6794888061.681271751.5636235572.094342170.600194283-0.379303875-0.581994949
223108-0.185242983-0.3777489280.802891924-0.9108416510.2840252030.56191761.4251485950.241537070.130058727-0.007731881-0.286864111.2742928870.7600557560.963080535-0.1318184610.1168581570.151746238-0.2600793710.0996124280.4345282260.3016785781.1564873832.451111041
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12013 is not tested in classification assay
Integrated Annotations for CG12013 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
response to lipid hydroperoxideGO:0006982inferred from sequence or structural similarity with UniProtKB:P36969
oxidation-reduction process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from sequence or structural similarity with UniProtKB:P36969
mitochondrion
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
peroxidase activityGO:0004601inferred from direct assay
glutathione peroxidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG12013 in FlyBase
FLIGHTClick here to see CG12013 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12013 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12013
Entrez GeneEntrez Gene page for CG12013
UniprotUniprot page for CG12013

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)