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Gene Page - CG Number : CG12014
Gene Summary - CG12014:

CG12014: This gene is referred to in FlyBase by the symbol Dmel\CG12014 (FBgn0035445). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: iduronate-2-sulfatase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Sulfatase; Sulfatase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.

Gene summary for CG12014 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12014:CG12014 is not perturbed in primary screen.
CG12014 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12014.
Cell Count:
CG_NumberCategoryR1R2R3
CG12014Primary screen22918174
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12014:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22159-0.5240604430.1714754810.57307272-0.3291203430.5528195060.5632108440.3697213750.522087811.2255569932.5945713681.772029297-0.4970590651.6515765230.853394875-0.270194521.7741018861.4726352851.3764672261.497663861.3405631332.792126073-0.1191905751.819596035
2221970.608683064-0.644551253-0.140147240.584303812-1.396821918-0.504615811-1.163631592-0.531320044-0.70624005-0.2554972910.6883938150.6352566920.1630556760.120917702-0.158546656-1.759674416-0.799205005-0.89058164-1.252156874-0.252814165-0.2958257620.639145218-0.193171593
223107-0.636537063-1.067901233-0.759032353-1.806856605-3.613341523-3.356115456-2.717108153-3.599261604-4.50138856-0.646250286-3.287876411-1.028800025-2.624389784-3.177187816-0.452416063-3.475561774-2.85835134-2.509912871-3.992239843-4.39773041.3324103330.161758020.97377368
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12014 is not tested in classification assay
Integrated Annotations for CG12014 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
metabolic processGO:0008152inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
iduronate-2-sulfatase activityGO:0004423inferred from sequence or structural similarity with UniProtKB:P22304
Other annotations
DatabaseLink
FlyBaseClick here to see CG12014 in FlyBase
FLIGHTClick here to see CG12014 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12014 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12014
Entrez GeneEntrez Gene page for CG12014
UniprotUniprot page for CG12014

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)