Gene Page - CG Number : CG12015

Gene Summary - CG12015:

CG12015: The gene RabX6 is referred to in FlyBase by the symbol Dmel\RabX6 (CG12015, FBgn0035155). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activity; GTP binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: small GTPase mediated signal transduction. 8 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG12015 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG12015:

CG12015 is not perturbed in primary screen.
CG12015 is not tested in classification assay.

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG12015.

Cell Count:

CG_Number	Category	R1	R2	R3
CG12015	Primary screen	185	189	161

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG12015:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
22	1	60	-0.006838316	0.045449876	-0.213282048	1.586	-1.205785929	-1.314251115	-1.122459862	-1.206433416	-1.408531571	0.149390254	0.406783682	0.541715383	0.8787347	0.624759865	-0.595562472	-0.059433773	0.50977305	0.301742727	0.191523738	-1.082818418	-0.51443854	1.030511728	1.635540907
22	2	196	-0.22806307	0.317125802	0.045366397	0.142974992	-2.554422262	-1.187094464	-1.649750034	-1.180287098	0.273333755	-0.226048165	-0.332285605	-0.206900994	0.866259065	0.947112334	0.117736682	0.356919043	0.353904001	1.683979002	0.520549518	0.381435118	-0.13640458	-0.072575126	-0.172596472
22	3	106	1.404122068	0.235904556	-0.241326881	0.470815651	0.077020379	-0.003646068	0.352507581	0.150833173	0.074762429	-0.105898332	0.17507946	0.407989875	1.040267591	0.407833043	-0.84474355	0.344422862	0.206430146	0.170799646	-0.075203151	0.054948145	-0.00522934	-0.69260498	-0.066393387

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

CG12015 is not tested in classification assay

Integrated Annotations for CG12015 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
small GTPase mediated signal transduction	GO:0007264	inferred from electronic annotation with InterPro:IPR001806

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
-

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
GTP binding	GO:0005525	inferred from sequence or structural similarity with UniProtKB:P53994 GTPase activity

Other annotations

Database	Link
FlyBase	Click here to see CG12015 in FlyBase
FLIGHT	Click here to see CG12015 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG12015 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG12015
Entrez Gene	Entrez Gene page for CG12015
Uniprot	Uniprot page for CG12015

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Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)