Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG12019
Gene Summary - CG12019:

CG12019: The gene Cdc37 is referred to in FlyBase by the symbol Dmel\Cdc37 (CG12019, FBgn0011573). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: unfolded protein binding. There is experimental evidence that it is involved in the biological process: neurogenesis. 20 alleles are reported. The phenotypes of these alleles are annotated with: actomyosin contractile ring; rhabdomere; adult abdomen; spermatid; spindle; nucleus. It has one annotated transcript and one annotated polypeptide. Protein features are: Cdc37; Cdc37, C-terminal; Cdc37, Hsp90 binding; Cdc37, N-terminal domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG12019 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12019:CG12019 is not perturbed in primary screen.
CG12019 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12019.
Cell Count:
CG_NumberCategoryR1R2R3
CG12019Primary screen115233311
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12019:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22162-0.3782652810.1556171170.0098032390.465538667-1.20104722-1.770306116-1.781939868-1.952882019-1.6760297451.7544931471.366777333-0.906312120.7610050711.2653250560.9009131930.290555482-0.1173279410.374967004-0.993966686-1.4502633490.57051279-0.601556841-0.706681748
222224-0.452016607-0.6254305980.541406006-0.1456451960.5952946521.281169872.7800872770.9908481381.1272767110.3624062780.390266474-0.3315751940.8691926271.104217943-0.5508364080.4372715960.7368770.6216374680.8188567121.2304722820.244515226-0.6114629440.703345511
223740.090342572-0.5398037860.4699929170.2845634951.9137646482.4400625375.4766037913.0129768573.3856688830.3041214872.967315614-0.7666246840.9342008581.5845709840.1480716752.424797862.5694508121.6859645692.4405923183.7705070960.380825189-0.394375841-0.107693942
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12019 is not tested in classification assay
Integrated Annotations for CG12019 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
intracellular protein kinase cascadeGO:0007243non-traceable author statement
transmembrane receptor protein tyrosine kinase signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
chaperone bindingGO:0051087non-traceable author statement
protein tyrosine kinase activator activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG12019 in FlyBase
FLIGHTClick here to see CG12019 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12019 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12019
Entrez GeneEntrez Gene page for CG12019
UniprotUniprot page for CG12019

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)