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Gene Page - CG Number : CG12030
Gene Summary - CG12030:

CG12030: The gene UDP-galactose 4'-epimerase is referred to in FlyBase by the symbol Dmel\Gale (CG12030, FBgn0035147). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: UDP-glucose 4-epimerase activity. There is experimental evidence that it is involved in the biological process: galactose metabolic process. 9 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: NAD(P)-binding domain; NAD-dependent epimerase/dehydratase; Nucleotide sugar epimerase; UDP-glucose 4-epimerase; UDP-glucose 4-epimerase C-terminal domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 12-24 hour embryonic stages, during late pupal stages, in adult male stages.

Gene summary for CG12030 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12030:CG12030 is perturbed in following parameters in primary screen: Fint1
CG12030 is perturbed in following parameters in classification assay (fluid): SP_Fint1- SP_Fnum-
CG12030 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12030.
Cell Count:
CG_NumberCategoryR1R2R3
CG12030Primary screen215286238
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12030:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221694.6146478880.594397838-0.511254928-0.4220631740.5284781250.8663796491.6763291670.5181730710.7320191240.4107856790.952324539-0.1185408541.3926955112.34828574-0.2638286390.7584384160.7861755390.7352093310.807837030.8476589370.3680204980.0142882851.956148885
222217-0.41912643-0.299726064-0.3137853690.2323715661.0495262360.917860330.9263509351.09408181.1980633420.4605256880.0213507470.187202510.6690497550.3149929270.0921498851.4828538421.1129552821.526020231.509010681.3224947020.1426649130.8827548960.349861658
223675.4385458572.9323088130.275884078-0.3056489231.2568681772.2071903485.342401242.8271534052.8908404260.221431787-0.357497264-0.3676256161.7331786241.490316949-0.2526815432.0841822151.5535829073.3089110641.7139843183.2662544771.3341577412.4033421812.702326008
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG12030Slide21C0.1841.0411.7751.434
CG12030Slide21O0.1650.5240.4520.518
CG12030Slide21P0.4580.9511.2271.177
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG12030 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
galactose metabolic processGO:0006012non-traceable author statement
galactose metabolic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
UDP-glucose 4-epimerase activityGO:0003978inferred from sequence or structural similarity with SGD_LOCUS:GAL10; SGD:S0000223
UDP-glucose 4-epimerase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG12030 in FlyBase
FLIGHTClick here to see CG12030 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12030 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12030
Entrez GeneEntrez Gene page for CG12030
UniprotUniprot page for CG12030

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)