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Gene Page - CG Number : CG12031
Gene Summary - CG12031:

CG12031: The gene Mediator complex subunit 14 is referred to in FlyBase by the symbol Dmel\MED14 (CG12031, FBgn0035145). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; RNA polymerase II transcription cofactor activity. There is experimental evidence that it is involved in the biological process: transcription from RNA polymerase II promoter. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Mediator complex, subunit Med14. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.

Gene summary for CG12031 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12031:CG12031 is not perturbed in primary screen.
CG12031 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12031.
Cell Count:
CG_NumberCategoryR1R2R3
CG12031Primary screen31294149
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12031:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22170-0.0437541892.7880809963.0345404680.676390281.3082879242.021123972.0610165041.5606657922.529514920.8346524491.045310714-0.5367075980.9923243080.8038655320.1829352633.2113048094.11881214.461359412.7974445242.5428104240.872483662-0.8026838952.404680498
222216-0.2263923590.327251214-0.351790972-0.807054634-1.932683989-1.582943603-1.863294159-1.659425819-1.795412111.297667702-0.3357755881.34939816-0.531146667-0.4793123960.837680606-1.399261047-0.8442030160.524260751-1.054991867-1.656506677-0.273301753-0.221701888-0.83512415
22366-0.2774466561.4134521892.5642858261.030337189-1.515319687-2.173577029-0.797004547-2.284260182-5.10247927-1.397616065-0.390894706-0.648987237-2.061673919-2.8802561090.064046247-6.644530314-4.168395836-1.850521044-7.828972014-4.840662075-0.1724790671.1624187843.817659461
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12031 is not tested in classification assay
Integrated Annotations for CG12031 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transcription from RNA polymerase II promoterGO:0006366inferred from mutant phenotype
transcription initiation from RNA polymerase II promoter
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634non-traceable author statement
mediator complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with UniProtKB:Q8MSX2
RNA polymerase II transcription cofactor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG12031 in FlyBase
FLIGHTClick here to see CG12031 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12031 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12031
Entrez GeneEntrez Gene page for CG12031
UniprotUniprot page for CG12031

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)