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Gene Page - CG Number : CG12051
Gene Summary - CG12051:

CG12051: The gene Actin 42A is referred to in FlyBase by the symbol Dmel\Act42A (CG12051, FBgn0000043). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of cytoskeleton. There is experimental evidence that it is involved in the biological process: cytokinesis; phagocytosis, engulfment. 10 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic tergum; trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Actin, conserved site; Actin-like; Actin/actin-like conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.

Gene summary for CG12051 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12051:CG12051 is not perturbed in primary screen.
CG12051 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12051.
Cell Count:
CG_NumberCategoryR1R2R3
CG12051Primary screen28234140
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12051:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22179-0.235916472-0.2790263830.2998093471.038367186-2.887922319-7.317822872-6.493574929-7.763260054-7.381519177-2.214354783-3.458856517-1.157509213-0.84062553-0.8766811710.40833929-6.076520223-5.588716165-5.152886682-6.336775823-6.9367893275.796959795-0.763323180.505918842
2222372.581553191.480561272-0.142259521.528885278-0.916510179-0.329825432-0.317208983-0.2885322060.9051195810.9682747940.1250933050.4981417990.8956902031.072743214-0.2091730080.909324861.8842316271.0814733251.1433199880.960273151-0.365634263-0.111355058-0.297998541
22387-0.881980071-0.0889794480.602997242-0.800920615-0.6848759920.0033905682.020860313-0.441120014-0.791276602-0.581432522-0.2479202690.3652674691.1096031790.545671208-0.022558873-1.154228609-1.022167268-0.515998775-1.32733715-0.3128982830.4757618650.3114827080.395197564
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12051 is not tested in classification assay
Integrated Annotations for CG12051 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
cytoskeleton organizationGO:0007010inferred from sequence or structural similarity
cytokinesis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
actin filamentGO:0005884inferred from sequence or structural similarity
actin filament
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
structural constituent of cytoskeletonGO:0005200inferred from sequence or structural similarity
ATP binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG12051 in FlyBase
FLIGHTClick here to see CG12051 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12051 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12051
Entrez GeneEntrez Gene page for CG12051
UniprotUniprot page for CG12051

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)