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Gene Page - CG Number : CG12061
Gene Summary - CG12061:

CG12061: This gene is referred to in FlyBase by the symbol Dmel\CG12061 (FBgn0040031). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: calcium, potassium:sodium antiporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 2 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Sodium/calcium exchanger membrane region; Sodium/potassium/calcium exchanger. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed during late pupal stages, in adult male stages.

Gene summary for CG12061 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12061:CG12061 is not perturbed in primary screen.
CG12061 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12061.
Cell Count:
CG_NumberCategoryR1R2R3
CG12061Primary screen2026268
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12061:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221830.597820748-0.4902519031.5325514740.006654712-0.457654102-2.2140598330.98808612-3.782853572-0.743857844-0.951416073-0.9350083282.32890868-0.387421677-1.38942405-0.334840863-0.2620474830.104411004-0.61666867-0.015215272-0.792765837-0.7484380340.5443012190.821543606
2222331.2885333081.532555645-0.068656717-0.024892153-2.780718026-1.540890473-0.131080416-1.866183563-2.9289344811.896653569-3.857550630.232608983-1.150125966-1.5734067980.824410538-1.697047935-1.485242739-0.319328558-2.010420624-2.6595390190.4818752880.7327131040.45250519
223830.0580729070.6486826340.5668362660.614869918-3.030817573-2.566464992-0.44023714-3.213187399-5.182472299-1.214909717-2.826436789-1.074117044-2.218657202-3.222526477-0.634755967-7.097746945-6.072392455-4.219159859-8.397495599-4.8702275770.294467661-0.713145692-0.720177868
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12061 is not tested in classification assay
Integrated Annotations for CG12061 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transmembrane transportGO:0055085inferred from electronic annotation with InterPro:IPR004837
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from electronic annotation with InterPro:IPR004837
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
calcium, potassium:sodium antiporter activityGO:0008273inferred from sequence or structural similarity with EMBL:AF026132
Other annotations
DatabaseLink
FlyBaseClick here to see CG12061 in FlyBase
FLIGHTClick here to see CG12061 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12061 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12061
Entrez GeneEntrez Gene page for CG12061
UniprotUniprot page for CG12061

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)