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Gene Page - CG Number : CG12065
Gene Summary - CG12065:

CG12065: This gene is referred to in FlyBase by the symbol Dmel\CG12065 (FBgn0030052). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: catalytic activity. There is experimental evidence that it is involved in the biological process: lateral inhibition. 6 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Nucleoside phosphorylase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages.

Gene summary for CG12065 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12065:CG12065 is perturbed in following parameters in primary screen: Fmph2
CG12065 is perturbed in following parameters in classification assay (fluid): NuCirc+(fld) NuFluct-(fld) NuSize-(fld)
CG12065 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12065.
Cell Count:
CG12065Primary screen139292368
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12065:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG12065 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
lateral inhibitionGO:0046331inferred from mutant phenotype
nucleoside metabolic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
catalytic activityGO:0003824inferred from electronic annotation with InterPro:IPR000845
Other annotations
FlyBaseClick here to see CG12065 in FlyBase
FLIGHTClick here to see CG12065 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12065 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12065
Entrez GeneEntrez Gene page for CG12065
UniprotUniprot page for CG12065

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)