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Gene Page - CG Number : CG12066
Gene Summary - CG12066:

CG12066: The gene cAMP-dependent protein kinase 2 is referred to in FlyBase by the symbol Dmel\Pka-C2 (CG12066, FBgn0000274). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: cAMP-dependent protein kinase activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine- / dual-specificity protein kinase, catalytic domain; Serine/threonine-protein kinase, active site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late pupal stages, in adult male stages.

Gene summary for CG12066 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12066:CG12066 is not perturbed in primary screen.
CG12066 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12066.
Cell Count:
CG_NumberCategoryR1R2R3
CG12066Primary screen157138217
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12066:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22186-0.635220010.138227193-0.489333415-0.436392809-2.541062708-3.09828741-1.800878033-3.398150532-0.7842898731.605953080.9722688370.607039958-0.1836316790.159092698-0.4680176321.0148903080.4376874570.1429969530.125838085-0.4168835330.0870677470.5147821970.540452506
222230-0.310900643-0.589933820.0697846081.124953363-0.761613475-0.0626935510.551257533-0.333583971-0.563564738-1.853025274-1.796524166-0.416677789-1.081048933-1.361908542-0.498947339-0.5914539280.588388484-0.077732066-0.285403039-0.392170126-0.512617006-0.0725485330.101461033
223800.3667894221.1098342041.893578450.3395608521.4674803311.4048042395.932020281.2431774730.965407877-1.1440560480.595885031.292614165-0.722399872-0.7363048890.331452888-0.083787297-0.101394964-0.283977616-0.0956332991.121352254-0.161453282-0.0329693931.028074445
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12066 is not tested in classification assay
Integrated Annotations for CG12066 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
protein phosphorylationGO:0006468inferred from sequence or structural similarity
protein phosphorylation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cAMP-dependent protein kinase complexGO:0005952inferred from sequence or structural similarity
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
cAMP-dependent protein kinase activityGO:0004691inferred from sequence or structural similarity
protein serine/threonine kinase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG12066 in FlyBase
FLIGHTClick here to see CG12066 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12066 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12066
Entrez GeneEntrez Gene page for CG12066
UniprotUniprot page for CG12066

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)