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Gene Page - CG Number : CG12076
Gene Summary - CG12076:

CG12076: The gene YT521-B is referred to in FlyBase by the symbol Dmel\YT521-B (CG12076, FBgn0027616). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: RNA binding. Based on sequence similarity, it is predicted to be involved in the biological process: RNA metabolic process. 7 alleles are reported. The phenotype of these alleles is annotated with: eye. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: YTH domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.

Gene summary for CG12076 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12076:CG12076 is not perturbed in primary screen.
CG12076 is not tested in classification assay (fluid).
CG12076 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fclc+ Fint1+ Fint2+ Fint3+ Fmph1+ Fmph3+ NuCirc+(tfr) NuFluct-(tfr) NuSize-(tfr) Tclc+ Tint1+ Tint2+ Tint3+ Tmph1+ Tmph2+ Tmph3+ Tnum+
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12076.
Cell Count:
CG_NumberCategoryR1R2R3
CG12076Primary screen101213139
CG12076Secondary assay7379641042
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12076:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
22196-0.893132197-0.2369152010.3872251511.217919002-3.872665767-5.236313705-3.780413021-5.587290058-4.140166634-1.647402586-1.468799271.395768846-1.765666929-0.802816368-0.681678448-2.641918526-2.454044344-2.465345958-2.682925223-3.658863253-0.929115318-0.270778683.448337973
222250-0.4650193620.0005977031.202520163-0.1362801890.0032745960.2985246681.0695369040.4274388750.584342752-0.232364098-0.215867574-0.1664959530.5612199040.328958647-0.093295207-0.1434899060.3557656080.7187612260.3342839190.918939745-0.359855102-0.235587123-0.283100368
22340-0.682334870.16189597-0.0227544370.003421265-1.456441253-1.328120751-1.527170978-1.259554408-1.371537324-0.285659167-0.732441544-0.549013021-0.172668757-0.848498258-0.533134736-0.715898471-0.778072837-0.152880338-0.958454186-1.402446562-0.232561623-0.4115324871.406590312
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG12076Slide13F0.0011.1581.2001.183
CG12076Slide13O0.1411.1681.1871.014
CG12076Slide13T0.0061.4151.3391.491
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG12076 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
RNA metabolic processGO:0016070inferred from sequence or structural similarity with RGD:Ythdc1; RGD:621706, GeneDB_Spombe:SPCC736.12c
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nuclear bodyGO:0016604inferred from sequence or structural similarity with RGD:Ythdc1; RGD:621706, GeneDB_Spombe:SPCC736.12c
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
RNA bindingGO:0003723inferred from sequence or structural similarity with GeneDB_Spombe:SPCC736.12c
Other annotations
DatabaseLink
FlyBaseClick here to see CG12076 in FlyBase
FLIGHTClick here to see CG12076 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12076 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12076
Entrez GeneEntrez Gene page for CG12076
UniprotUniprot page for CG12076

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)