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Gene Page - CG Number : CG1208
Gene Summary - CG1208:

CG1208: This gene is referred to in FlyBase by the symbol Dmel\CG1208 (FBgn0037386). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: glucose transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: General substrate transporter; Major facilitator superfamily domain; Major facilitator superfamily domain, general substrate transporter; Sugar transporter, conserved site; Sugar/inositol transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.

Gene summary for CG1208 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1208:CG1208 is perturbed in following parameters in primary screen: Fint2 Fint3 Fmph1 Fmph2 Tclc
CG1208 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fint2+ LP_Fint3+ Okt+(fld) Rto1+ Rto2+ Rto3+ SP_Fint1+ SP_Fint2+ SP_Fint3+ SP_Fmph1+ SP_Fnum+
CG1208 is perturbed in following parameters in classification assay (transferrin): Fclc- Fint1- Fint2- Fint3- Fmph1- Fmph2- Fmph3- Fnum- NuCirc-(tfr) NuFluct+(tfr) Rto2-(tfr) Rto3-(tfr) Tclc- Tint1- Tint2- Tint3- Tmph1- Tmph2- Tmph3-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1208.
Cell Count:
CG_NumberCategoryR1R2R3
CG1208Primary screen202722671
CG1208Secondary assay933596971
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1208:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1208Slide11C0.0151.2571.1681.184
CG1208Slide11O0.0181.3841.3361.201
CG1208Slide11P0.0561.5431.6601.211
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse


Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1208Slide2F0.0040.8610.7930.835
CG1208Slide2O0.1220.9690.9380.886
CG1208Slide2T0.0010.3430.5140.334
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG1208 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
transmembrane transportGO:0055085inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828, InterPro:IPR005829
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from electronic annotation with InterPro:IPR005828
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
glucose transmembrane transporter activityGO:0005355inferred from sequence or structural similarity with MGD:Slc2a3; MGI:MGI:95757
Other annotations
DatabaseLink
FlyBaseClick here to see CG1208 in FlyBase
FLIGHTClick here to see CG1208 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1208 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1208
Entrez GeneEntrez Gene page for CG1208
UniprotUniprot page for CG1208

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)