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Gene Page - CG Number : CG12085
Gene Summary - CG12085:

CG12085: The gene poly U binding factor 68kD is referred to in FlyBase by the symbol Dmel\pUf68 (CG12085, FBgn0028577). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: mRNA splicing, via spliceosome; cystoblast division; mRNA splice site selection; regulation of cell growth; alternative mRNA splicing, via spliceosome; regulation of cell cycle; regulation of alternative mRNA splicing, via spliceosome; neurogenesis. 16 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; adult segment; organ system subdivision; thoracic segment; external compound sense organ; imaginal precursor; cytoplasmic part; karyosome; embryonic/larval imaginal precursor; cell cortex part. It has 10 annotated transcripts and 10 annotated polypeptides. Protein features are: Nucleotide-binding, alpha-beta plait; Poly-U binding splicing factor, half-pint; RNA recognition motif domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG12085 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG12085:CG12085 is not perturbed in primary screen.
CG12085 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG12085.
Cell Count:
CG_NumberCategoryR1R2R3
CG12085Primary screen22519366
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG12085:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
221103-0.671899291-0.0954866971.27659602-0.8891328070.6152721111.5432735993.2964867381.2134042651.086746462-0.0080949430.169059663-0.4796632160.4693394980.8172757990.4536388350.6579734490.6276191250.4457955830.8760689421.2445979130.188171367-0.4177288280.403406347
2222431.2863979081.062117591-0.3366198690.2814813850.1235079150.7487992252.6239364810.8337689380.692341413-0.302334253-0.407796640.3599719171.0186557331.407642927-0.0843128090.2548568690.3933049210.7348328320.6011989550.6928145260.413857488-0.009381607-0.601629897
223332.6597637061.026578343-0.285623432-1.201510626-2.976892831-2.3761012240.833591758-2.848085493-4.94240735-3.173514263-1.7362071694.79795594-0.05681232-3.509043182-0.282289624-5.840402436-4.945724848-2.657221818-7.179093396-4.7337168710.7031258220.3449269250.467678606
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG12085 is not tested in classification assay
Integrated Annotations for CG12085 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
nuclear mRNA splicing, via spliceosomeGO:0000398non-traceable author statement
nuclear mRNA splicing, via spliceosome
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from direct assay
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
poly(U) RNA bindingGO:0008266non-traceable author statement
mRNA binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG12085 in FlyBase
FLIGHTClick here to see CG12085 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG12085 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG12085
Entrez GeneEntrez Gene page for CG12085
UniprotUniprot page for CG12085

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)